PLLAV Concept

The PLLAV Concept. The full infectious lifecycle of the commercial  YFV-17D vaccine (step 1-4). Transfection of PLLAV-YFV-17D bypasses the need for infectious thermo-labile LAVs yet results (following steps 2-4) in the formation of a replicating vaccine virus in the vaccinated host that is identical (but yet a clonal variant) to (of) the commercial LAV.


PLLAV: “combining the best of both worlds”